Cardio Congress

Introduction: The word dystrophy comes from the roots of Latin and Greek that means "the defective nutrition". When the doctors began first to describe the muscle diseases to the nineteenth century, they had few other tools their own eyes. The muscles in a lot of diseases seemed to be the waste far, and the doctors theorized that they properly were not nourished of a manner or of another. Today, we know that a lot of diseases of waste of muscle are caused by the defects in the genes for the muscle proteins. Most of these proteins appear to play a role in to support the structure of fibers of muscle, although some proteins can play a role in the biochemical processes that continue in the muscle fibers. The Muscular dystrophy of term refers itself to a group of genetic diseases marked by weakness and the progressive degradations of the of skeletal or voluntary muscles that check the movement. The muscles of the heart and some other involuntary muscles also are affected in some forms of muscular dystrophy, and some forms imply other organs also. The major forms of muscular dystrophy are myotonic, Duchenne, Becker, the member belt, facioscapulo-humeral, congenital, oculo-pharangeal, distal and emeri-dreifuss. Certain of these names are based on the locations of affected muscles. For example, facioscapulo-humeral refers itself to the muscles that move the face, the shoulder blade (the shoulder blade) and the humedrus (the arm bone). Of others are based on the type of problem of muscle implied ("myotonic" means difficulty to relax the muscles), the age of beginning of the disease (as in "congenital," or the birth beginning, the dystrophy), or the doctors that first described the disease (Duchenne, Becker, the Emeri and Dreifuss are names of the doctors). The forms of muscular dystrophy differ in the severity, the beginning age, the first muscle and most often affected, the rate to that the symptom progress, and the manner that the disorders is inherited. The muscular dystrophy is diagnosed by muscle biopsy, the essay of DNA, the edlectromyogramme (E M G) and the velocity of conduction of nerve (N C V). The tests of enzyme of blood are muscle serviables because degenerating that becomes it "pierced". They flee enzymes, that then can be detected in the blood. The presence of these enzymes in the blood to more than normal top the levels are a sign of muscular dystrophy. The such a enzyme is Creatine kinase, or CK. The CK levels student in a lot of forms of muscular dystrophy, some forms that have for result a higher level than of others.



The muscular dystrophy of Duchenne (DMD) is the X LINKS UP mortal the most common the disorder redcessif, affecting 1 in 3,500 male births in life (1). The children of DMD show early symptoms of degradation of muscle, frequently to develop spasms, and lose the capacity to walk between 6 and 12 major years. With the progressive disease, most of the patients succumb to the death of respiratory failure and to cardiac malfunction in their twenty (2). The primary cause of these stems of disease of the mutations in the gene of dystrophin, that is essential for structural and functional integrity muscles (3). The mutations in dystrophin have for result the damages of membrane, allowing the massive infiltration of immunized cells, the chronic inflammation, necroses it, and the degradation of harsh muscle (2). Normally, the muscle cells possess the capacity to regenerate in response to the injury signals. Nevertheless, this capacity is lost in DMD, probably because of a cell exhaustion by satellite during the continuous degradations and of cycles of regeneration (1). Although the mutations of dystrophin represent the primary cause of DMD, it is the secondary processes that imply the persistent inflammation and the reduced regeneration that probable worsens the disease progression. DMD is characterized by (I) the Beginning of weakness of muscle of ordinary one before 4 major years, (II) the engagement of Selective muscle of belts pelviennes and pectoral, (iii) the Hypertrophy of the muscle of calves, (iv) student crudely of the levels of K OF C of sedrum and (v) Implacably progressive weakness of muscle, take to the inability to work in 10 years of beginning and late to the spasms and to the deformity Thoracique. There is not specific remedy in any system of medicine and the death of ordinary one arrives before the age of 20 years caused by respiratory failure or less frequently by the cardiac engagement. (4)



The muscular dystrophy of Becker (BMD) was described at first by Becker and Kiener in 1955.(5, 6). The signs, the symptoms and the course of muscular dystrophy of Becker (BMD) are similar to those of Duchenne but appears generally and progresses later more slowly. BMD is generally more soft than DMD. The distinction clinic between the 2 conditions is comparatively easy because (I) the weakness of less than harsh muscle is observed in the patients with BMD and (II) affected maternal uncles with BMD continue to be outpatient after having ages 15-20 years. Diagnosis precision was refined with the recognition of the defects of gene of dystrophin and with dystrophin stains specimens of biopsy of muscle. (3, 4, 5). The dystrophy of Becker can appear first a lot later than Duchenne, even as last as to age 25. The progression is typically slower, with the capacity to walk of ordinary preserved one in to the years 30. The severity of the disease varies, and the boys and the men with the dystrophy of Becker have a longer life length than those with Duchenne. The weakness progression depends on how much dystrophin is done and how well it works in the muscles.



The member belt dystrophies muscular (L G M D) are disorders neuromusculaires characterized by close muscular weakness of the belts pelvien and of shoulder and a variable progression with the symptoms, spreading of very harsh one to soft (7), (4). The beginning of Muscular dystrophy of Belt of Member (L G M D) is generally in the adolescence or early the adult age. In most of the common forms, L G M D causes progressive weakness that begins in the hips and transfers to the shoulders. Weakness progresses to include the arms and the legs. In 20 years of beginning, the walk is difficult. The researchers found that autosomal the dystrophy of member belt redcessive can result from the gene defect on the chromosomes 2, 13, 15, and 17, and that an autosomal forms it dominating can result from the gene defects on the chromosome 5. A gene on the chromosome 15 that code for the enzyme calpain 3 can play also a role in certain cases of L G M D.



Pathogenesis: The dystrophy is a genetic defect and is caused by the lack of a Dystrophin of protein of only muscle (1 of 3000 proteins of muscle). DMD and BMD are because of the different changes in the gene of dystrophin, that contains the news for a protein that is important for the muscle cells to work properly. This gene is localized on the chromosome of X. Dystrophin is localized to the sarcolemma in the normal skeletal muscle, but is completely absent in the muscle of the patients of DMD (8). Of ordinary the disease is inherited but also is caused by the spontaneous mutation more than 30% of the time. Every child of the mother of carrier has a 50% chance of inheritance of Muscular dystrophy. Although the girls can be carriers, more than 80% spectacle than no muscular dystrophy related symptoms. To present a hypothesis applies a defect in the membrane of sarcolemma that allows a substance (or the substances), so far unknown but that probably could be calcium, enter the muscle fiber also freely, and there activate neuter proteases that, in the bend, maintain an excessive degree of catabolism of muscle and takes to necroses it fiber of muscle. (9, 10, 11, 12).



No treatment is in this known moment in any system of medicine that has any defined influence on the muscular dystrophy. The absence of treatment specific for the brands of muscular dystrophy it so much more important to consider supplementary and alternate approaches of treatment. In India, the boys of Dystrophy always look for the assistance of Ayurvedic in the hope for some relief. The treatment of Ayurvedic that implies the group of Rasayana of herbo-minedral or of now based medicine, the support of yogic and the procedures of karma of specific Panch showed influences it defined protective and the longer survival on the muscular dystrophy. Ayurvedic Acharyas considers carefully this condition as adibala-pravrit Mamsa-vata-kshaya because of srotorodha. There is the exhaustion of pave of Mamsagni the manner of formation of American medical Assocation. It is followed by vitiation of Kapha dosha. (13, 14, 15). While the products of srotorodha hypertrophient in the special region, it shows also as first prokopa and then the exhaustion of element of Vata. This complex pathogenesis is responsible of the waste and of necroses it progressive of the affected fibers of muscle.



Ayurveda envisions 13 major types of Agnis (the enzyme complex) that are responsible of the process of metabolism. Each of seven dhatus has individual dhatvagnis. The increase or the special decrease of a dhatus depends on the increase or the decrease of respective dhatvagnis. According to Charak, mamsa-kshaya can be present when there is extended majjagata kupita Vata. This always is followed by the exhaustion of element of Vata. It is the genetic predisposition (Beeja dosha) that converts the element of Vata physiologique in to the pathological morbid character. The srotodushti (? The defect of membrane of Sarcolemma) is responsible of the mamsa dhatu kshaya.



The dosha-mauvais concept by Dhatu (D. D. M) is unique in Ayurveda. The dhatus is these substances that are kept by the body and always rejuvenated or full. Ras-Rakta-Mamsa-Meda-Asthi-Majja and Sukra is seven dhatus that develops in the human body in a manner sets up and sequential the one of the other. Every following dhatu is a refinement of the metabolism of the preceding dhatu and is nourished by him. The first dhatu, Shaves (the nutritious liquid) is produced it end of the metabolism of the digestion that intervenes in the gastrointestinal range. The dhatu Shaves must be transformed by metabolism in to Rakta dhatu. The Mamsa dhatu comes from Rakta dhatu and in the bend, generate dhatu to Meda. The Asthi dhatu is produced it Meda dhatupaka that contains Majja dhatu that is the essential seat of element of Vata. (13, 15)



We know that Vata (Prana) and Rakta dhatu is two major lives that supports elements in the body. The Vata was attributed as genetic equipment that carries the essential element of information of life for the different activities. The Rakta dhatu is the basis of biological force that furnishes the nutrition at the cell level and paves the manner of excretion of toxins of metabolism. The driving force beyond Rakta dhatu is the element of Vata that circulates itself at the cell level with Rakta. The joint circulation of Rakta and Vata is the life demonstration (Prana). This Prana is responsible of the contraction and relaxation of fibers of muscle or muscular activity. It means that we must converge our attention on the dhatvagnis paka of dhatus of Rakta of Mamsa Shaves and Meda besides Asthi and Majja dhatus. In this therapy of Rasayana of Ayurvedic of context has the significant role to play. (16, 17) the Old doctors of Ayurvedic had developed process of degradation of stop/delay of measure and rejuvenate certain dietary and therapeutic functional entire the dynamics of the system of body. This restarts and the rejuvenation are as knowledges the 'Rasayana Chikitsa' (rejuvenation therapy). Rasayana is the special resources of ayurvedic that increase the enzymatic gasoline of every dhatu begin dhatu Shaves. The usages of Ayurveda the source to plant basis, minerals and metallic to this effect. Traditionally, the drugs of Rasayana are used against a plethora of in various appearance disorders with no connections patho-physiologiques according to modern medicine. Nevertheless, this plant group generally possesses strong activity of antioxidant, few was examined in detail. The diseases of Neurodegenerative were retrieved as the oxygen type revives acted in mediator and several plants of Rasayana with the activity of powerful antioxidant were informed by a lot of investigators (18). The bhasma in now pure in the low dose was used with success in the direction of degenerative diseases of mamsa and Majja dhatu. (19, 20, 21). The certain known grasses of Ayurvedic for their effects of Rasayana scientifically are verified for their possible effect in the direction of Muscular dystrophy. Famous grass Tumeric widely followed was examined for the immuno-localisation and the activation of nuclear factor-

{Kappa} B in polymyositis, dermatomyositis, and the muscular dystrophy of Duchenne (DMD). Do the data support the hypothesis that NF-? B contributes to the perpetuation of the damages of dystrophic and shows that his blockade produces advantageous effects on the functional, biochemical parameters and morphologiques. These new conclusions can have implications clinics for the treatment pharmacologique of patients with the Muscular dystrophy. (22, 23, 24, 25, 26). Withania somnifera is the grass of wonderful ayurvedic that widely is used for tension, the functions of resistance and brain. It contains Withanolide that is anti-arsonist; induced the significant regeneration of let us center, dendrites, the pred-synapses and the post synapses in the neurones. It eliminates the free radical generation; It improves also neuronal malfunction. (27), (28) (29). The cardiac problems associated with forms of muscular dystrophy sometimes treatment of need. Terminalia Arjuna has remarkable cardio protectif, the heart muscle strengthens property. The current scientific research proved this plant contains constituent medically specific active to knowledge triterpine glycosides as arjunetosides I, II, III, IV, arjunine and arjunetein, phytosterols, rich in the minerals as calcium, magnesium, zinc and the copper. The uniform usage of Arjuna improves pumping the heart activity, improves the force of cardiac muscle, the decrease in the levels of cholesterol of LDL. It was retrieved to possess protectif cardio-vasculaire and the property of hypolipidemic. (30). Of same Tinospora cordifolia was used in general debility, the disturbances liqueurs, the loss of appetite and the fever in the children. This is also an effective immunostimulant. Its constituent principal one are tinosporine, tinosporide, cordifolide, and cordifol. The plant is used in Ayurvedic Rasayana to improve the immunized system and the resistance of the body to the infections (31). The being of Praval a natural source of rich calcium, charred Coral widely is used in the medicine of ayurvedic as a supplement in the treatment of variety of bone disorders of metabolism associated with the calcium lack. Praval bhasma is effective in the obstacle of calcium spasms insufficient vertebral and bones deformities (32).



Of ordinary the molecule of Rasayana does not work without the procedures of purificatory. The deepana, the process of pachana must be strengthened, the dosha must be balanced of the and the toxins of metabolism must be eliminated dhatus by the procedures of karma of Panch in the order for the molecule of Rasayana to work (33), (35). The support of Yogic always is found useful in the direction of Muscular dystrophy. The collection of Pawanamuktasa of Asanas of Yoga and of Bhastrica Pranayama is important, especially when the dystrophy progressed for several years. Breathing deeply and laugh often is recommended optimizing the respiratory care (19, 20).



Equipment &the amplifier; the Methods: Keep in looks at the complex pathogenesis implied in the Muscular dystrophy, a supplement of Rasayana of Ayurvedic of special one was developed using deepan-pachan one-srotorodhahara and the resources of Ayurvedic of vardhak of dhatu of mamsa. The supplement developed and named as Mamsagni Rasayana. It combines the advantageous effects proved of Tumeric followed, Withania somnifera, Tinospora cordifolia, Terminalia Arjuna, charred Coral (Praval) and Now bhasma, any treaty in fresh juice of aloe vera barbendensis. The dose of the Mamsagni Rasayana was repaired 20 mg by the weight of body of kilo. The drug orally was managed in two equal doses after the meal with 100 ml of milk for a period of 6 months.



More than 100 case of Muscular dystrophy were registered to the Clinic of Karma of Panch of Central Medical Institute, Bhilai and treated during March 1999 and September 2004. We chose total 28 boys of DMD, 19 boys of BMD and 8 boys of LMGD for the inclusion in our study clinic. All the boys of Dystrophy were liable to 2 weeks Panch the procedures of karma before the administration of Mamsagni Rasayana oral with the support of Yogic for 6 months. The treatment program that consists in (I) Modified A To Dough Pinda Swedana using of the fresh leaves of Tejapatra (Cinnamomum tamala), Nirgundi (Vitex negundo) and pushed Methi (Trigonella foenum) the seeds as the additional ingredients to Even To, Masha, the non polite rices and the wheat sound, all cooked one in the brew of Bala (Aids cordifolia), Ashwagandha (Withania somnifera) and the milk. (II) Anuvasana Vasti with the shatbala-prasarni oil. A mixture of Oil of Sesame 80%, the oil of Soja 10% and Roulette oils 10% was used as the disgusting oil that was meddiqued by the standard method. Principal grasses used in the oil preparation are Shatavari (racemosus of Asparagus), Bala (Aids cordifolia), and Ashwagandha (W. somnifera), and Nirgundi (Vitex negundo), and Haridra (Tumeric domestica), and Daru Haridra (epine-vinette aristata), and Mustaka (Cyperus rotundus), and Barbreng (teasing Embelia), and Mamsa Rohini: (Soymida febrifuda). These grasses are used as the tonic Neuromusculaire because of their property of balance of Vata.



The observation &the amplifier; Results: In our study, the functions motors were evaluated the usage score motor total, the degrees of function of superior extremities and lower and the timed tests of function. The inability was quantitated with the index of Barthel. The children were found to have inabilities in the multiple spheres of life, that was influenced in a significant way by the strength motor. The index of Barthel was useful in to identify and quantifying of the specific sectors of inabilities in these children.
It was observed that the degradation of fibers of muscle was stopped after 6 weeks of administration of Mamsagni Rasayana. This was presumed while basing itself on reduced CK levels in the blood, the capacity and the functional qualities improved of life. All the boys of Dystrophy that completed Etude clinic signs defined showed of improvement as: (I) the weight loss, (II) the Decrease in the walk of difficulty and (iii) the Decrease in the severity of spasms and of scoliosis. Nevertheless the boys of DMD showed the very slow progress.



Discussion: Today we know that the muscle the degenerative conditions of waste in the young patients are caused by the defect in the genes for the muscle proteins. Most of these proteins appear to play a role in to support the structure of fibers of muscle, although some game a role of biochemical enzymes. DMD and BMD are caused by the lack of protein of dystrophin. The drugs of Rasayana of Ayurvedic are well known for their effect for delay/slows down or reverses the progressive muscular degradation. (14), (18), (20) (22) (34) (38). Certain of the ingredients of Mamsagni Rasayana scientifically were verified for their influence protective possible in the muscular dystrophy (21-29). The Mamsagni Rasayana is supposed to raise Mamsagni at the level of muscle fabric. It balances the disturbance of Vata because of American medical Assocation and delays thus the muscular degradation because of American medical Assocation (the big deposition). The To masha Pinda Swedana stabilizes and improves the membrane defect removes the fatty additional one fabric. The Anuvasana Vasti balances the element of Vata. The support of Yogic of collection of Muktasana of Pawan minimizes the spasms, a condition associated often with the muscular dystrophy in which shortened muscles around the joints cause the abnormal and sometimes painful position of the joints. Besides, Pawan Muktasana with certain other Asanas as Bhujangasana can prevent or can delay the scoliosis, or the curvature of the thorn. The Bhastrika Pranayama can support Cardio- the Respiratory system and can improve the process of silly oxidation at the cell level. Since we noticed the functional capacity improved with a fall in the sedrum Creatine kinase (CK) levels the means that there is the check on the amplest destruction of muscle.



Summarized:



The muscular dystrophies are genetic disorders with no satisfactory treatment in any system of medicine. This is a disease muscle progressive wasting because of a mutation in the gene of dystrophin and the lack of consequent protein in the muscle. It has for result the chronic inflammation and muscle harsh skeletal degradation. How the lack of the dystrophin of protein of sarcolemma generates to the statute of final disease is not yet clear. Several proofs suggest a role of decontrol of nf-kappa in the muscular dystrophy. The nuclear blockade of kappa-b of factor reduces the degradation of skeletal muscle and improves the muscle function. The regulation &the amplifier; the check of NF? B is thus important. Should the treatment of Swedana of Pinda of Dough of ayurvedic with the resources of herbo-minedral of Rasayana be examined to the light of possible influence on the membrane of Sarcolemma and NF? B: the blockade. In this context research aimed is necessary to identify the grasses of sure ayurvedic, the techniques of Yogic and the ampler procedures of karma of Panch to improve the supplementary approach of Ayurveda. The program of Ayurvedic is useful in the direction in the long term of muscular dystrophies. There is more the need of controlled studies and of multi essays clinics of center on a big ladder with the conception of improved studies and the evaluation techniques.



References:-


1. Blake, D. J.; Weir, A.; Newey, ITSELF. ; Davy, K. E. (2002) the Function and the genetic one of proteins of dystrophin and dystrophin-related in the muscle. Physiology. Rev. ; 82:291ae"329.



2. The emery, A. E. (2002) : The muscular dystrophies. Lancet. 359:687ae"695.



3. Dalkilic, I.; Kunkel, L. Mr. Mr. (2003) Muscular dystrophies: the genes to the pathogenesis. Curr. Opin. Genette. Dev. ; 13:231ae"238.



4. John Walton and David Gardener medwin (1988) The Muscular Dystrophies; In: The disorders of Voluntary Muscles, Ed: Mister Walton (fifth Edn), Churchill Livington.



5. Becker PE, Kiener F. (1955) A new muscular dystrophy chromosome x. Curve Psychiatr Nervenkr Z Gesamte Neurol Psychiatr. ; 193(4):427-48.



6. Becker PE. (1962) : Two families of benign linked sex the muscular dystrophy redcessive. Biol. of Can of Rev; 21:551-66.



7. Bushby, K. Mr. D. &THE amplifier; Beckmann, J. S. (1995) : The member belt the muscular dystrophies ae” the suggestion for a new nomenclature. Neuromusc, Disord. 5, 337-343.



8. Kevin P. Campbell (1995) Three Muscular Dystrophies: Reconsider Loss of Link of Matrix cytoskeleton-extracellulaire, the Cell, Flight. 80, 675-679.



9. Mokri B, Engel AG (1975) : The dystrophy of Duchenne: the edlectron conclusions microscopiques that indicate to a basic or first abnormality the membrane of plasma of the fiber of muscle, the Neurology 25: 1111



(10) Rowland IP (1976) : The pathogenesis of muscular dystrophies. The archives of Neurology 33: 315



(11) the S of Ebashi, Sugita O'CLOCK (1978) : The calcium Role in the processes physiologiques and pathological of skeletal muscle. The fourth International Congress on the Diseases Neuromusculaires, Montreal.



(12) Wakyama THERE, Bonilla E, Schotland DL (1983) : The abnormalities of membrane of plasma in the babies with DMD. The neurology (Cleveland) 33: 1368-1370



(13) Nair P Ramchandran and Al (1980) : The muscular dystrophy of pseudo-hypertrophie- One Approach Ayurvedic. The newspaper of Res. In Ayurveda &the amplifier; Siddha 1:3 (429-437)



(14) Jain Mukesh D (2000) : Genetic Muscular dystrophy. The Madhurima (Weekly Bhaskar) May 2000



(15) Charak Samhita, Chikitsa Sthana 28:14, the Office of Collection of sanscrit of Chaukhambha, Varanasi, India



(16) Bhaishajya Ratnavali, Comm. A D Shastri, the Office of Collection of sanscrit of Chaukhambha, Varanasi (1991)



(17) Sagar Shaves yoga, the Academy of Krishnadas, Varanasi (1983) V0l I &the amplifier; II



(18) R. Govindarajan, Mr. Vijayakumar and P. Pushpangadan (2005) : The approach antioxidant to the direction of disease and the role of grasses of "Rasayana" of Ayurveda; the Newspaper of pharmacology of Ethno. Flight 99:2, 165-178



(19) Jain Mukesh D (2001) the Muscular dystrophy- Ek Jatil Roga. Newspaper Nirogadham 23:1 (81-82)



(20) Jain Mukesh D (2001) Fights His Dystrophy Now! Day. N I M AN India 43:5(5-7)



(21) Gada Nigraha: The Office of Collection of sanscrit of Chaukhambha, Varanasi (1968)



(22) Majeed M, Badmaev V, Shivkumar U, Rajendram R (1995) : Curcumoids-antioxydant. Phytonutrients, the Editeurs of Nutriscience, New Jersey (p 40)



(23) Mr. C. Monici, Mr. Aguennouz, and Al. (2003) : The activation of MD of nuclear factor- {kappa} B in inflammatory myopathies and the muscular dystrophy of Duchenne; the Neurology 2003;60:993-997



(24) Durham W J.; Arbogast and Al (2006) : The progressive nuclear factor-? the activation of resistant B to the inhibition by the contraction and curcumin in the mice of mdx; the Muscle &the amplifier; the nerve, 2006, flight. 34:3, 298-303



(25) Chiara Mozzetta, G Minetti, P Lorenzo Puri (2009) : The regenerative pharmacology in the treatment of genetic diseases: The paradigm of muscular dystrophy, The International Newspaper of Biochemistry &the amplifier; the Biology of Cell, the Volume 41, the Problem 4, April 2009, Asks 701-710



(26) Deepa Thaloor, Kristy J. Miller and Al (1999) : The administration of the system of the curcumin of suppressant of B of nf-kappa stimulates the muscle regeneration. .., Is Physiol of Cell of Physiol of J 277: C320-C329.



(27) Tohda C, Kuboyama T, Komatsu K (2005) : Look for natural products linked to the regeneration of the neuronal network. Neurosignals. 14(1-2):34-45.

(28) Kuboyama T, Tohda C, Komatsu K. (2005) : The regeneration neuritique and reconstruction synaptique induced by Withanolide A. J Pharmacol British. 2005 avr; 144(7):961-71.

(29) Zhao J, Nakamura N, Hattori M and Al. (2002) : The drifts of Withanolide of the roots of Withania somnifera and their activities of excrescence of neurite. The Bull of Pharm of Chem (Tokyo). 50(6):760- 5

(30) Alpana Rowed, P. Bay leaf, R Gupta, and Al (1997) : The effects of Hypocholesterolaemic of Terminalia Arjuna, the Newspaper of pharmacology of Ethno, Flight 55:3, 1997, Asks 165-169

(31) the S OF S. OF SINGH, THE S OF PANDEY and Al. (2003) : Chemistry &the amplifier; the Medicinal property of Tinospora cordifolia. Indian newspaper of Pharmacology. 35: 83-91

(32) Reddy P.N. ; Lakshmana Mr.; Venkatesh U. (2003) : The effect of Praval bhasma (calx of Coral), a natural source of rich calcium on bone mineralization in the rats. The research pharmacologique; 48:6, pp.593-599

(33) Jain Mukesh D, Annapurna of Yoga, Pandey MP (2002) : Preliminary Etude of Approaches Integrated of karma of Panch, the Medicine of Yoga and Ayurvedic in the Direction of Muscular Dystrophy: 46 Patients. The world-wide Magazine of Health, 1:1 (33-35)



(34) Jain Mukesh D (2003) : Ayurvedic Direction of Muscular dystrophy of Duchenne: A research report: Light on Ayurveda, the Newspaper of Health, the winter problem 2, Mashpee (WORE)



(35) Jain Mukesh D (2005) : The Karma of Panch &the amplifier; the Direction of Yogic of Muscular dystrophy: Scientific newspaper of Karma of Panch &the amplifier; Arogyadham January 45-47



(36) Jain Mukesh D (2005) the Direction of Ayurvedic of Muscular Dystrophy. Global Ayurveda Flight. 1:3 (24-29)



(37) Jain Mukesh D. (2006) : Mamsagni Rasayana in the treatment of Muscular Dystrophy of Duchenne: 28 Patients. Ayurvedic Patrika Nasik (MS) India Flight. 4:3; 54-59



(38) Jain Mukesh D. (2008) : New Advances in the Care of Ayurvedic of ailments Neuromusculaires. Global Ayurveda, Flight. 4:5; 36-50-66

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Author:

Dr Mukesh Jain is the director of Program of Clinic of Karma of Panch on the Diseases Neuromusculaires to Bhilai of Hospital of Ayurvedic of Sanjivani. It is the known practicien of Karma of Panch of Ayurvedic since 1981, doubles has measuring: in the Basic Sciences, Ayurveda with Medicine and modern Surgery the two of Saugar &the amplifier; the Universities of Shankar of Delight; It is the scientific author of two books on Ayurveda &the amplifier; the Yoga; upon the advice of editorial of Global Ayurveda, the Magazine of World-wide Health &the amplifier; Light on the Newspaper of Ayurveda ; It is President of Corporation of Muscular Dystrophy of AYUSH a charter of India of CG of Bhilai of Samiti of Ayush.

http://openlibrary.org/a/OL4097418A

Address for the communications &the amplifier; the questions:

Mukesh D Jain

6/5 Is Priyadarshani, Supela 490023 Bhilai, India

The e-mail: mjainbhilai@gmail. the com

The telephone; 0788-2392358 Cells 0-9826180335


The following graphic pictures are not posted:

1. Result Analyzes on the improvement in the Functional capacity (the Echelle of Barthel)

2. The improvement clinic after 6 months.
3. The quality of improvement of Life.

The fig 2 Result Analyzes Functional capacity (the Echelle of Barthel)

The fig 3 Improvements Clinic after 6 Months

The fig 4 Qualities of Improvement of Life


The news as for updated it research are subjected to the National Center for Supplementary and parallel Medicines

Nccam. nih. gov/prepared.


It is interested completely and enough well does for the science of ayurvedic. The paper is recommended to the group of lecture of NAMA.
Dr. Marc Halpern
President California University of Ayurveda, WORE


Interest the study and well does with that. Dispatched to the president of the scientific committee of the association of practiciens of Ayurveda, Dr Eduardo cardona-sanclemente.

Dr. Donn Brennan
The president, Association of Practiciens of Ayurveda, United Kingdom


The well described approach from the standpoint of CAM. There is the possibility to do a request of the benefits of research to NCCAM that will facilitate to return bigger a the project to the ladder.
Teacher. Mr. S. Rao, Sc.D.
Howard Univ. Collar. Of Medicine
Washington, DC